Conjugué médicament-polymère à base de copolymère à partir d'iso-oléfines

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专利权人:

Lanxess Inc.;The University of Western Ontario

发明人:

申请号：

EP14195663.1

公开号：

EP3028719A1

申请日:

2014.12.01

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

A polymer-drug conjugate, which can be used in medical applications such as stents, has at least one active agent conjugated through a carboxylic acid moiety to a copolymer derived from at least one isoolefin monomer and at least one copolymerizable monomer, where the copolymerizable monomer is at least one multiolefin monomer, a β-pinene monomer or a mixture thereof. Such conjugates show improved adhesion to stainless steel and a substantial decrease in burst release of paclitaxel form a drug eluting stent (DES).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/