Provided are anti-PD-L1 antibodies, variants, mutants, and antigen binding fragments thereof. Also provided are isolated nucleic acid molecules that encode the anti-PD-L1 antibodies, variants, mutants, or antigen binding fragments thereof, and related expression vectors, and host cells. Provided are methods of making anti-PD-L1 antibodies, variants, mutants, and antigen binding fragments thereof. Also provided are related pharmaceutical compositions and methods of their use to treat subjects.本發明提供抗-PD-L1抗體、其變異體、其突變體、及其抗原結合片段。亦提供編碼抗-PD-1抗體、其變異體、其突變體、或其抗原結合片段之經單離核酸分子，以及相關表現載體，及宿主細胞。提供製造抗-PD-1抗體、其變異體、其突變體、及其抗原結合片段的方法。亦提供相關醫藥組成物及其使用於治療個體的方法。
