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Microencapsulated probiotic substance and manufacturing process
专利权人:
Vesale Pharma Sa;Brace GmbH
发明人:
QUINTENS, Johan Henri Herman,LIENART VAN LIDTH DE JEUDE, Jehan,BRANDAU, Thorsten,STROHM, Holger,SCHWINN, Jens
申请号:
ES12700703
公开号:
ES2627858T3
申请日:
2012.01.20
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
A dry powder composition comprising solid particles containing: a) a live probiotic microorganism, b) a carrier phase in which said live probiotic microorganism is encapsulated, said carrier phase comprising at least one substance chosen from the group consisting of alginate, chitosan, pectin, pululane, gelatin, carrageenan, agar, said carrier phase comprising an enteric composition and further comprising at least one nutritional source comprising at least one compound chosen from the group consisting of a monosaccharide, a polysaccharide, an amino acid, a peptide, a protein, a vitamin, a yeast extract, a halogen salt of an alkaline or alkaline earth metal, an antioxidant, glycerol, zinc acetate, zinc chloride, zinc lactate, ascorbic acid, citric acids or a vegetable oil and milk fat, characterized in that said dry powder composition has a particle size distribution that between n and (n + 400) μm, where n is between 100 and 10,000 μm, preferably between 300 and 5000 μm, more preferably between 400 and 1000 μm and because said solid particles are spherical particles comprising from 50 to 80 % of said live probiotic microorganism and that said dried powder composition can be obtained by drip molding in laminar flow.Una composición de polvo seco que comprende partículas sólidas que contienen: a) un microorganismo probiótico vivo, b) una fase portadora en la que dicho microorganismo probiótico vivo está encapsulado, comprendiendo dicha fase portadora al menos una sustancia elegida entre el grupo constituido por alginato, quitosano, pectina, pululano, gelatina, carragenano, agar, comprendiendo dicha fase portadora una composición entérica y comprendiendo además al menos una fuente nutritiva que comprende al menos un compuesto elegido entre el grupo que consiste en un monosacárido, un polisacárido, un aminoácido, un péptido, una proteína, una vitamina, un extracto de levadura, una sal halógena de un metal alcalino o alcalinotérreo, un antioxidante, glicerol, acetato de c
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