Comprehensive nutrition powder and a preparation method therefor. The comprehensive nutrition powder is characterized by comprising the following raw materials: vitamin B1, vitamin B2, vitamin B6, pantothenic acid, vitamin B12, vitamin C, vitamin A, vitamin K, vitamin D, vitamin E, biotin, folic acid, calcium, magnesium, iron, zinc, selenium, chromium, copper, manganese, corn fiber flour, inulin, soy isolate protein powder, black bean peel extract, Agaricus blazei Murill extract, soya bean lecithin, phaseolus calcaratus extract, L-carnitine, ß carotene, lycopene, citrus extract, vanadium, acerola cherry extract, grape seed extract, maltodextrin, essence, aspartame and acesulfame. The comprehensive nutrition powder is a nutrition-rich food that is researched for special purposes, and can match low sugar diet and moderate exercise, so as to form a regulation scheme that specially aims at regulating obesity as well high blood pressure, high blood sugar and high blood fat.