Philip Robert JACKSON,Mark CRESSWELL,Ian F. CAMPBELL
申请号:
US16834640
公开号:
US20200222390A1
申请日:
2020.03.30
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Porous particles comprising an active ingredient and a coating exhibiting greater dissolution rate in aqueous media than in alcoholic media are disclosed. A process for the manufacture of the particles is also disclosed, as well as tamper-proof particles and solid dosage forms comprising the coated particles. The differential solubility characteristics of the particle coating allow low the particles to be incorporated into abuse-deterrent medicaments.