MicroRNA as a cancer progression predictor and its use for treating cancer

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专利权人:

发明人:

申请号：

EP12160692.5

公开号：

EP2505645B1

申请日:

2012.03.22

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention is based on the findings that a novel function for miR142-3p in the regulation of Sox2, adenylyl cyclase 9 (AC9), and CD133 expressions, and consequently the overall stemness of recurrent GBM cells as well as CSCs, and that miR142-3p modulated tumor-initiating properties in recurrent GBM. The present invention consequently supports the development of novel miRNA-based strategies for brain tumor treatment.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/