Angela Norton,Michael F. Concino,Muthuraman Meiyappan,Andrea Iskenderian
申请号：
US14763783
公开号：
US10729746B2
申请日:
2014.01.28
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides, among other things, methods and compositions for treating muscular dystrophy, in particular, Duchenne muscular dystrophy (DMD). In some embodiments, a method according to the present invention includes administering to an individual who is suffering from or susceptible to DMD an effective amount of a recombinant PLGF protein such that at least one symptom or feature of DMD is reduced in intensity, severity, or frequency, or has delayed onset. The present invention also provides exemplary recombinant PLGF proteins including monomeric, dimeric and single-chain PLGF proteins.
