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Kidney specific tumor vaccine directed against kidney tumor antigen G-250
专利权人:
Arie Belldegrun;Cho-Lea Tso
发明人:
Arie Belldegrun,Cho-Lea Tso
申请号:
US12479415
公开号:
US08741306B2
申请日:
2009.06.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
This invention provides an anti-cancer immunogenic agent(s) (e.g. vaccines) that elicit an immune response specifically directed against renal cell cancers expressing a G250 antigenic marker. Preferred immunogenic agents comprise a chimeric molecule comprising a kidney cancer specific antigen (G250) attached to a granulocyte-macrophage colony stimulating factor (GM-CSF). The agents are useful in a wide variety of treatment modalities including, but not limited to protein vaccination, DNA vaccination, and adoptive immunotherapy.
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