A device for preventing the spread of disease especially in healthcare and food handling facilities by making it very quick and easy to disinfect hands without having to take extra steps. A small, disinfectant-filled bottle, typically flat, that fits snugly to the waist on a belt, or attached to a pocket, allows almost instantaneous disinfecting of hands simply by reaching down and spraying a small amount of disinfectant fluid on the hand while walking, standing or performing just about any other task. Being generally light and smooth, the device resists hanging up on material or objects, and it can be worn by both male and female personnel. A concave valve prevents false spraying. When empty, the device can be disposed of without any messy refilling.