N-[2-(PIPERIDIN-1-YL)PHENYL](PHENYL)METHYL-2-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXA ZIN-7-YL)ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ROR-GAMMA MODULATORS FOR TREATING AUTOIMMUNE DISEASES
DELHOMEL, Jean-Fran‡ois,PERSPICACE, Enrico,MAJD, Zouher,PARROCHE, Peggy,WALCZAK, Robert
申请号:
PH12019501684
公开号:
PH12019501684A1
申请日:
2019.07.22
申请国别(地区):
PH
年份:
2020
代理人:
摘要:
The present invention provides e.g. N-{[2-(piperidin-1-yl)phenyl] (phenyl)methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)acetamide derivatives and related compounds as ROR-gamma modulators for treating e.g. autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases or cholestatic diseases, such as e.g. arthitis and asthma.