VIEIRA ERIC,GUBA WOLFGANG,RICCI ANTONIO,JOLIDON SYNESE,RUEHER DANIEL,STADLER HEINZ,LINDEMANN LOTHAR,JAESCHKE GEORG,GREEN LUKE
申请号:
NZ60102411
公开号:
NZ601024A
申请日:
2011.04.11
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed herein are arylethynyl derivatives of formula (I), wherein the variables shown in formula (I) are as defined in the specification. These arylethynyl derivatives are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5) and are useful for the treatment of schizophrenia, cognitive diseases, fragile X syndrome or autism.