Yen-Ta LU;Mackay Medical Foundation The Presbyterian Church In Taiwan Mackay Memorial Hospital
发明人:
Yen-Ta LU,Chia-Ming CHANG,Tsai-Yin WEI
申请号:
US15735949
公开号:
US20180141991A1
申请日:
2016.06.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A method for modulating an immunoresponse includes binding a TREM-like transcript 1 (TLT-1) polypeptide to an immune cell, wherein the binding of the TLT-1 polypeptide to the immune cell suppresses immunoresponse. A method for treating and/or preventing a disease associated with immune hyper-reactivity includes administering the TLT-1 polypeptide to a subject in need thereof.