ELLINGHUYSEN, JERRY, A.,FILBURN, CHARLES,GRIFFIN, DAVID,HENDERSON, TODD, R.
申请号:
EP07754571
公开号:
EP2010220A4
申请日:
2007.04.03
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Various pentosan polysulfate (PPS) formulations useful for treatment of osteoarthritis, interstitial cystitis, and other conditions of mammals are provided. These formulations showed improved resistance to degradation and discoloration and improved stability at physiological pH, even after sterilization. Capillary electrophoresis analysis of these formulations indicates that various formulations remain stable under conditions that caused degradation of PPS in prior art PPS formulations.