ANTAGONISTE PEPTIDIQUE DU RECEPTEUR ALPHAVBETA3 SELECTIF UTILISE DANS DES APPLICATIONS THERAPEUTIQUES ET DE DIAGNOSTIC

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专利权人:

ADVANCED ACCELERATOR APPLICATIONS

发明人:

申请号：

EP06806112.6

公开号：

EP1934248B1

申请日:

2006.10.09

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention is related to new peptide antagonists of alphavbeta3 receptor, designed on the basis of the crystal structure of integrin alphavbeta3 in complex with c(RGDf[NMe]V) and the NMR structure of echistatin. These peptides are potent and selective antagonists of the alphavbeta3 receptor and can be used as novel anticancer drugs and/or new class of diagnostic non-invasive tracers as suitable tools for alphavbeta3-targeted therapy and imaging.

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中国工程科技知识中心

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http://www.ckcest.cn/home/