潘托拉唑（ＰＡＮＴＯＰＲＡＺＯＬＥ）多粒型調配物农业专利-农业学术服务平台

发明人:: VENKATA RAMANA RAO, SRIPRIYA,斯里布利亚文卡塔拉曼纳劳,斯里布利亞文卡塔拉曼納勞,SHAH, SYED M.,塞德Ｍ　夏,TATAPUDY, HANUMANTHARAO,汉努曼沙劳塔塔普迪,漢努曼沙勞塔塔普迪,SAUNDERS, RICHARD WILLIAM,理查威廉桑达斯,理查威廉桑達斯,FAWZI, MAHDI,马迪佛兹,馬迪佛茲,塞德M 夏

摘要：: Pantoprazole sodium multiparticulates are described which avoid sticking to nasogastric and gastronomy tubes. The pantoprazole multiparticulates have a spheroid core of pantoprazole or an enantiomer thereof, or a salt thereof, a surfactant, and a disintegrant； a sub coat which is comprised of hydroxypropyl methylcellulose (hypromellose) and water, an enteric coat on the sub-coat, and a final seal coat over the enteric coat, which is composed of hydroxypropyl methylcellulose (hypromellose) and water.本發明係說明一種潘托拉唑鈉(Pantoprazole Sodium)多粒物，其可避免黏附至鼻胃管及食道管(gastronomy tube)。該潘托拉唑多粒物具有由潘托拉唑或其鏡像異構物，或其鹽，以及界面活性劑構成之球狀核心；次塗層(sub coat)，其係由羥丙基甲基纖維素(羥丙甲纖維素(hypromellose))及水組成，次-塗層上之腸衣(enteric coat)，以及腸衣外之最終密封塗層(final seal coat)，其係由羥丙基甲基纖維素(羥丙甲纖維素)及水組成。