Bernard Christophe Barlaam;Laurent Francois Andre Hennequin;Robert Hugh Bradbury
发明人:
Laurent Francois Andre Hennequin,Bernard Christophe Barlaam,Robert Hugh Bradbury
申请号:
US13607999
公开号:
US20120329795A1
申请日:
2012.09.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention concerns quinazoline derivatives of Formula I:wherein each of R1, X1, R2, R3, R5, n and m have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of EGF and erbB receptor tyrosine kinases.