PROBLEM TO BE SOLVED: To provide a therapeutically effective amount of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine or a pharmaceutically acceptable salt thereof for treatment of irritable bowel syndrome.SOLUTION: A pharmaceutical composition is administered in a crystalline form of a HBr addition salt of the specified compound characterized by peaks in an XRPD at approximately 6.08, 14.81, 19.26 and 25.38° 2&thetas; (all ±0.1°). A medical treatment includes administration of the compound of 1-20 mg/day.【課題】過敏性腸症候群の処置における4-[2-(4-メチルフェニルスルファニル)フェニル]ピペリジン又は医薬的に許容できるその塩の治療有効量の提供。【解決手段】下記化合物のHBr付加塩がXRPDにおける約6.08、14.81、19.26及び25.38°2θ(全て±0.1°)のピークを特徴とする結晶形で投与される医薬組成物。前記化合物が1~20mg/日投される、医療的処置。【選択図】なし