THE TEXAS A&M UNIVERSITY SYSTEM;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
发明人:
John R. Barta,Luc Berghman,Srichaitanya Shivaramaiah,Olivia B. Faulkner,Lisa Bielke,Billy Hargis
申请号:
US15877598
公开号:
US10328137B2
申请日:
2018.01.23
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Vaccine vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or mortality associated with subsequent infection are provided herein. The vaccine vectors include a polynucleotide encoding a Rhomboid polypeptide and optionally include an immune-stimulatory polypeptide suitably expressed on the surface of the vaccine vector.