Cosmetic facial treatment delivery sheets with both personalized skincare benefit agents and customized iontophoresis micro-current zones are provided for delivering skincare treatments to multiple targeted areas of the skin to treat different concerns of an individual user. The sheets are made by printing skin benefit agents on a dissolvable or non-dissolvable substrate and then printing micro-current generators with power sources in different locations on the substrate. The micro-current generators facilitate delivery of the benefit agents by iontophoresis, or directly affect treatment by delivery of micro-current to the skin.
