Chun-Ching SHIH,Jin-Bin WU,Yueh-Hsiung KUO,Cheng-Hsiu LIN,Hui-Ya HO
申请号：
US14882890
公开号：
US20170105953A1
申请日:
2015.10.14
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided is a method for suppressing diabetes and/or hepatic lipids in a mammal to lower blood glucose levels and hepatic total lipids and triacylglycerol contents by increasing AMP-activated protein kinase (AMPK) phosphorylation in both skeletal muscle and liver tissue, and Akt phosphorylation and membraneprotein levels of glucose transporter 4 (GLUT4) in skeletal muscle. The method comprises administrating to the mammal an effective amount of tormentic acid or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
