Maurice Raymond Verschoyle FINLAY,Frederick Woolf GOLDBERG,Attilla Kuan Tsuei TING
申请号：
US15846679
公开号：
US20180194782A1
申请日:
2017.12.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The specification generally relates to compounds of Formula (I):and pharmaceutically acceptable salts thereof, where R1 and R2 have any of the meanings defined herein. The specification also relates to the use of such compounds and salts thereof to treat or prevent DNA-PK mediated disease, including cancer. The specification further relates to pharmaceutical compositions comprising such compounds and salts； kits comprising such compounds and salts； methods of manufacture of such compounds and salts； intermediates useful in the manufacture of such compounds and salts； and to methods of treating DNA-PK mediated disease, including cancer, using such compounds and salts.
