PROBLEM TO BE SOLVED: To provide an easily practicable drug delivery system by solving a conventional technical problem by imparting magnetism to a short-chain RNA (siRNA), an anticancer agent and an in-vivo marker.SOLUTION: There is provided a compound represented by the formula, and obtained by binding a nucleic acid or a medicament through a silane coupling agent to an inorganic compound such as iron oxide and cobalt oxide. [In the formula, M is an inorganic compound such as iron oxide, chromium oxide, manganese oxide, cobalt oxide and nickel oxide R1 is hydrocarbon and X is a nucleic acid or a medicament such as ibuprofen and an amino acid].COPYRIGHT: (C)2013,JPO&INPIT【課題】短鎖RNA(siRNA)、抗がん剤、生体内マーカーに磁性を付与することで従来の技術的問題を解決でき、実用化が容易なドラッグ・デリバリ・システムを提供する。【解決手段】下式で示される、酸化鉄、酸化コバルト等の無機化合物にシランカップリング剤を介して核酸又は薬剤を結合させた化合物。[式中、Mは酸化鉄、酸化クロム、酸化マンガン、酸化コバルト、酸化ニッケル等の無機化合物を表し、R1は炭化水素基を表し、Xは核酸あるいはイブプロフェン、アミノ酸等の薬剤を表す。]【選択図】なし
