VERSTEGEN, IWAN,SONDERMEIJER, PAULUS JACOBUS ANTONIUS,VERMEIJ, PAUL
申请号:
PL15817860
公开号:
PL3185899T3
申请日:
2015.12.23
申请国别(地区):
PL
年份:
2018
代理人:
摘要:
The present invention regards a new and Improved HVT-vectored ND-IBD vaccine, comprising a recombinant HVT comprising the VP2 gene from IBDV and the F gene from NDV to a target animal. The recombinant HVT can be used in a vaccine for poultry, which displayed good viral vector replication, effective expression of the NDV F- and IBDV VP2 genes, improved immunoprotection against ND and IBD, and improved genetic stability over prior art constructs.