ДЗЕ ТРАСТИЗ ОФ ДЗЕ ЮНИВЕРСИТИ ОФ ПЕНСИЛЬВАНИЯ (US)
发明人:
РУК Ален Х. (US),ГЕЛФАНД Джоэл М. (US),ВЫСОЦКА Мария М. (US),БЕНУА Бернис М. (US),ТРОКСЕЛ Андреа Б. (US)
申请号:
RU2015132959
公开号:
RU2015132959A
申请日:
2014.01.06
申请国别(地区):
RU
年份:
2017
代理人:
摘要:
The present invention provides methods for treating a subject with cutaneous T cell lymphoma (CTCL). In certain embodiments, a subject is administered an effective amount effective of an IRM compound wherein at least one symptom or clinical sign of CTCL is ameliorated. The present invention further includes a method of increasing a cell-mediated immune response of a cell population that includes cells affected by CTCL. In certain embodiments, an effective amount of the cell population is contacted with an IRM compound wherein at least one cell-mediated immune activity of the cell population is increased.