NATIONAL UNIVERSITY OF IRELAND, GALWAY; GALWAY;GLYCOSENSORS AND DIAGNOSTICS, LLC.;UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.;NATIONAL UNIVERSITY OF IRELAND
发明人:
WOODS, ROBERT J.,MURPHY, PAUL V.,YANG, LORETTA,HENDEL, JENNIFER,SMITH, HANNAH M. K.,HENDEL, JENIFER
申请号:
CA2865627
公开号:
CA2865627A1
申请日:
2013.03.14
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention relates to novel glycomimetic compounds that are rationally designed to inhibit the binding of various pathogens to cell surface sialylated galactose and methods of use thereof. Specifically sialic acid glycosides and C-glycosides are disclosed that form a lactam ring structure or a cyclic ether/amine ring structure with the adjacent monosaccharide residue.