BUCHDUNGER ELISABETH,CAPDEVILLE RENAUD,DEMETRI GEORGE DANIEL,DIMITRIJEVIC SASA,DRUKER BRIAN JAY,FLETCHER JONATHAN A.,JOENSUU HEIKKI,SILBERMAN SANDRA LETA,TUVESON DAVID,HEINRICH MICHAEL C.
申请号：
CZ20031152
公开号：
CZ303944B6
申请日:
2001.10.26
申请国别(地区):
CZ
年份:
2013
代理人:
摘要：
Pouzití 4-(4-methylpiperazin-1-ylmethyl)-N-(4-methyl-3-((4-pyridin-3-yl)pyrimidin-2-ylamino)fenyl)benzamidu vzorce I nebo jeho farmaceuticky prijatelné soli pro prípravu léciva pro lécení gastrointestinálních stromálních tumoru, pricemz výhodné je pouzití slouceniny vzorce I ve forme monomethansulfonátové soli, zejména ve své beta krystalické forme.In the present invention, there is disclosed the use of 4- (4-methylpiperazin-1-ylmethyl)-N- [4-methyl-3- (4-pyridin-3-yl) pyrimidin-2-yl- amino) phenyl]-benzamide of the general formula I or a pharmaceutically acceptable salt thereof for the preparation of medicaments intended for the treatment of gastrointestinal stromal tumors, whereby the preferred use of the compound of the general formula I is in the form of monomethanesulfonate salt, particularly in beta crystalline form thereof.
