An automated reloading system for replacing a spent surgical end effector in a manipulatable robotic tool portion of a robotic surgical system is disclosed. The automated reloading system comprises a drive assembly configured to generate rotary drive motions and a selectively movable support assembly defining a plurality of end effector reloading positions. Each reloading position being configured to support a new surgical end effector or a spent surgical end effector therein. The selectively movable support assembly being further configured to selectively serially move each reloading position into a driving position wherein the new surgical end effector or the spent surgical end effector therein is configured to selectively receive the rotary drive motions. The automated reloading system further comprises means for releasably locking the movable support assembly in the driving position during the application of the driving motion to the new surgical end effector or the spent surgical end effector.