LI, John,CHEN, Mingjiu,TAN, Wei,TANG, Yong,LI, Shengwei,ZHOU, Ming
申请号：
AU2019254215
公开号：
AU2019254215A1
申请日:
2019.04.12
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
An isolated monoclonal antibody or an antigen-binding fragment that specifically binds human PD-1. A nucleic acid molecule encoding the antibody or the antigen-binding fragment, an expression vector, a host cell and a method for expressing the antibody or the antigen-binding fragment are also provided. The present invention further provides an immunoconjugate, a bispecific molecule, a chimeric antigen receptor, an oncolytic virus and a pharmaceutical composition comprising the antibody or the antigen-binding fragment, as well as a treatment method using an anti-PD-1 antibody of the invention.
