Cyclobutyl (S) -2-[[[((R) -2- (6-aminopurin-9-yl) -1-methyl-ethoxy] methyl-phenoxy-phosphoryl] amino] -propanoate and Its production process and application
The present invention relates to chemotherapeutic agents for the treatment of viral diseases and cancer. The compounds are prodrugs of DNA polymerase inhibitors of human immunodeficiency virus (HIV), hepatitis B virus (HBV) and human immunodeficiency virus, hepatitis B virus and HIV / HCV. , Is intended to treat co-infection of HIV / HBV, HIV / HCV / HBV and HCV / HBV.본 발명은 바이러스 질병 및 암의 치료를 위한 화학요법제제들에 관련된 것이다. 상기 화합물들은 인간 면역결핍 바이러스 (human immunodeficiency virus) (HIV), B 형 간염바이러스(HBV)의 DNA 폴리머레이즈 (DNA polymerase) 억제제의 전구약물이며 및 인간 면역결핍 바이러스, B 형 간염바이러스 및 HIV/HCV, HIV/HBV, HIV/HCV/HBV 및 HCV/HBV의 동시-감염을 치료하려는 의도이다.
