MERCK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
发明人:
KAI DR. SCHIEMAN,CARL DR. DEUTSCH,GUENTER DR. HOELZEMANN,DANIEL DR. KUHN,ANSGAR DR. WEGENER,DOMINIQUE SWINNEN,HORACIO COMAS
申请号：
ARP130100705
公开号：
AR090240A1
申请日:
2013.03.05
申请国别(地区):
AR
年份:
2014
代理人:
摘要：
The compounds of the formula (1) where denotes r u00b9 AR, cohet or het； R u00b2 denotes h, ar u00b9, nhhet or het； r u00b3 or r u2074 denotes denotes h； h, a, ar u00b9, Het, Hal, nhar u00b9 or ar is phenyl or naphthyl CN； that is not replaced or is mono - or alkylated with Hal, CyC. [c] (r u00b3) u2082 u209aoa [c] (r u00b3) u2082 u209aoh, CN.Nhcohet u00b9, nhcoa nhco [C (r u00b3) u2082 u209acyc [c], with u2082 u209acyc (r u00b3)], [c] u209an (r u00b3) u2082 (r u00b3) u2082 [c] (r u00b3) u2082 u209ahet u00b9, nr u00b3so u2082a, so u2082n ( u2082 r u00b3), S (OR) u2099a, cohet u00b9 [, or (C r u00b3) u2082 u2098n (r u00b3) u2082] and / or [C (r u00b3) phenyl] u209ahet u00b9 u2082； ar u00b9 denotes is not replaced or is mono - or alkylated with Hal, Fen ILO, conh u2082 [C (r u00b3) u209aor u00b3 u2082], [c] u209an (r u00b3) u2082 (r u00b3) u2082 [C (r u00b3) u209acn u2082], [c] u209ahet u00b9 u2082 (r u00b3) and / or [c] u209ahet u00b9 u2082 (r u00b3)； het denotes furilo, tienilo, pirrolilo, imidazolilo pirazolilo,,Oxazolilo, isoxazolilo, oxadiazolilo, thiazolyl, triazolilo, tetrazolilo, piridilo, pirimidilo, piridazinilo, pirazinilo.Indolilo, isoindolilo, bencimidazolilo, indazolilo, quinolilo, 1.3 - benzo - dioxolilo, benzotiofenilo, benzofuranilo, imidazopiridilo, dihidroindolilo, 2,3 dihydro - benzo [1,4] dioxinilo or furo [3,2-b] piridilo is not replaced or is mono -, di - or trisustituido with Hal, [C (r u00b3 u2082 u209aor u00b3 []), (C r u00b3) u2082 u209an (r u00b3) u2082], [c] u209ahet u00b9 u2082 (r u00b3), no u2082, CN, (r u2076) u2082 [c] u209acoor u00b3, (r u00b3) u2082, nr u00b3coa, nr u00b3so u2082a, so u2082n ( u2082 r u00b3), S (OR) u2099a,Cohet u00b9 or [C (r u00b3) u2082 u2098n (r u00b3) u2082], or [c] u209ahet u00b9 u2082 (r u00b3) and / or u =； het u00b9 denotes dihidropirrolilo, pirrolidinilo, azetidinilo, oxetanilo, tetrahidroimidazolilo, dihidropirazolilo, tetrahidropirazolilo, tetrahidrofuranil
