A cleaning composition comprising: a disinfectant； and an antimicrobial component including a silane quaternary ammonium ion or salt thereof. The disinfectant can include ortho-phthalaldehyde, peracetic acid, glutaraldehyde, a phenol, sodium hypochlorite, hydrogen peroxide, among other disinfectants. Such other disinfectants include two or more of octyldecyldimethyl ammonium chloride, dioctyldimethyl ammonium chloride, didecyldimethyl ammonium chloride, and n-alkyl (C14 to C16) dimethylbenzyl ammonium chloride. The silane quaternary ammonium ion or salt thereof can be one or more of: 3-(trimethoxysilyl)propyldimethyloctadecyl ammonium ion, 3-(trimethoxysilyl)propyldimethyloctadecyl ammonium chloride, 3-(trihydroxysilyl)propyldimethyloctadecyl ammonium ion, or 3-(trihydroxysilyl)propyldimethyloctadecyl ammonium chloride. The silane quaternary ammonium ion or salt thereof can constitute 0.05% to 5% by weight of the cleaning composition. The phenol can constitute 0.10% to 2.0% by weight of the cleaning composition. The cleaning composition can further include a propellant, and the cleaning composition can be contained in an aerosol can.
