PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CANCER DISEASES CONTAINING THE FRUITS OF ACANTHOPANAX SESSILIFLORUS EXTRACTS, FRACTIONS, THE ISOLATED COMPOUNDS THEREFROM, OR THE PHARMACEUTICALLY ACCEPTABLE SALTS AS AN ACTIVE INGREDIENT
PURPOSE: A pharmaceutical composition containing Acanthopanax sessiliflorum seeman fruit extract, fraction, compound isolated from the same, or pharmaceutically acceptable salt thereof is provided to prevent and treat cancer with reduced side effect. CONSTITUTION: A pharmaceutical comosition for preventing and treating cancer contains Acanthopanax sessiliflorum seeman fruit extract as an active ingredient. The extract is methanol extract prepared by dipping Acanthopanax sessiliflorum seeman fruits in 70% ethanol, filtering, and concentrating by reduced pressure. The pharmaceutical composition contains Acanthopanax sessiliflorum seeman fruit fraction as an active ingredient. The fraction is prepared by fractioning the extract with ethyl acetate and n-butanol. The pharmaceutical composition contains compounds isolated from the fraction or pharmaceutically acceptable salt thereof as an active ingredient. The compound x is acanthosessilioside A of chemcial formula 1, acanthosessilioside I of chemical formula 2, or methyl acanthosessiligenin of chemical formula 3.본 발명은 오가피 열매 추출물, 오가피 열매 분획물, 이로부터 분리된 화합물 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 암 질환의 예방 및 치료용 약학적 조성물에 관한 것이다. 본 발명에 따른 상기 암 질환의 예방 및 치료용 약학적 조성물은 암세포의 증식 억제 활성을 가짐으로써 종래의 암 질환 치료제에 비해 천연물을 사용하여 부작용을 현저히 감소시킬 수 있다.
