3-(aryl or heteroaryl) methyleneindolin-2-one derivatives as inhibitors of cancer stem cell pathway kinases for the treatment of cancer

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专利权人:

发明人:

LI CHIANG J,LIU JI-FENG,LI WEI,GIBEAU AMANDA,ROGOFF HARRY,TSUBOI KATSUNORI,TAKANASHI YOSUKE,TOJO SHINGO,KODAMA TOMOHIRO,KUBOTA KATSUMI,KANAI TOSHIO

申请号：

IN3375/KOLNP/2015

公开号：

IN2015KN03375A

申请日:

2015.10.13

申请国别(地区):

IN

年份:

2016

代理人:

摘要：

24567The invention provides compounds of Formula I as inhibitors of cancer stem cells as well as cancer stem cell pathway kinase and other related kinases pharmaceutical compositions and uses thereof in the treatment of cancer or a related disorder in a mammal wherein i.a. R is an optionally substituted heterocycle or optionally substituted aryl and one of R R Rand R is a substituted heterocycle or substituted aryl.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/