Ira Jacob Fox,Aaron W. Bell,Taichiro N. Nishikawa,Alejandro Soto-Gutierrez,Yoram Vodovotz
申请号：
US14177928
公开号：
US09981048B2
申请日:
2014.02.11
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The presently disclosed invention is directed to the discovery that hepatocyte nuclear factor 4 alpha (HNF4α also known as NR2A1), a transcription factor, reverses hepatocyte dysfunction in an animal model of cirrhosis, resulting in improvement in hepatic function, treatment of cirrhosis, and prolonged survival.
