Willem P. Stemmer;Ian M. Brennan;Joshua Silverman;Volker Schellenberger;Chia-Wei Wang
发明人:
Joshua Silverman,Volker Schellenberger,Willem P. Stemmer,Chia-Wei Wang,Ian M. Brennan
申请号:
US13078499
公开号:
US08557961B2
申请日:
2011.04.01
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to compositions comprising alpha 1-antitrypsin linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in the treatment of alpha 1-antitrypsin-related diseases, disorders, and conditions.