Michiel Luc, Maria Van Gool,José Ignacio Andrés-Gil,Manuel Jesús Alcázar-Vaca,Guy Maurits R. Bormans,Sofie Jeanne Leopoldine Celen,Joost Verbeek
申请号:
US15533279
公开号:
US20180264147A1
申请日:
2015.12.02
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or in vivo and to precursors of said compounds.