The present invention addresses the problem of providing nasal drops which can achieve high absorption of oxytocin, which is a peptide hormone, an acid addition salt of oxytocin or a derivative of oxytocin or the acid addition salt through a nasal mucosa and which has less concerns about safety. The present invention is a pharmaceutical composition intended to be administered to a nasal mucosa, characterized by comprising oxytocin, an acid addition salt of oxytocin or a derivative of oxytocin or the acid addition salt and a carboxyvinyl polymer and having an osmotic pressure ratio of less than 1.本發明係以提供一種屬胜肽激素之催產素或者其酸加成鹽或該等之衍生物之從鼻黏膜的吸收性高，且在安全性方面之疑慮較少的滴鼻劑為目的。本發明為一種鼻黏膜投與用醫藥組成物，其特徵為包含催產素或者其酸加成鹽或該等之衍生物、及羧基乙烯基聚合物，且滲透壓比低於1。
