PROBLEM TO BE SOLVED: To provide a method for simply producing unpleasant taste-lowered pharmaceutical preparations.SOLUTION: A medicine having unpleasant taste is dissolved or suspended in a solution including a water-insoluble coating agent, then the resultant solution or the suspension is granulated by adding the solution or the suspension to silicic acid, and the like.COPYRIGHT: (C)2003,JPO【課題】不快味を低減化した製剤を簡便な製造方法で提供する。【解決手段】不快味を有する薬物を水不溶性コーティング剤溶液に溶解または懸濁し、その溶液または懸濁液をケイ酸類に加えて造粒する。