Chi-Ying Huang,Jane Hsiao,Pan-Chyr Yang,Meng-Hua Lee
申请号:
US14841727
公开号:
US20160120876A1
申请日:
2015.09.01
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to use of antipsychotic phenothiazine derivative for treatment of cancer. The invention also provides a use for manufacture a medicament, a pharmaceutical composition and a method for treating a cancer, and/or preventing or delaying cancer recurrence based on trifluoperazine. The invention further provides a use for manufacture a medicament, a pharmaceutical composition and a method for treating cancer based on thioridazine and its enantiomers. Additionally, the invention provides a use for manufacture a medicament, a pharmaceutical composition and a method for treating KRAS mutant NSCLC comprising thioridazine.