Fe(iii) complexes for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anaemias

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专利权人:

VIFOR (INTERNATIONAL) AG

发明人:

BARK THOMAS,BUHR WILM,BURCKHARDT SUSANNA,BURGERT MICHAEL,CANCLINI CAMILLO,DÜRRENBERGER FRANZ,FUNK FELIX,GEISSER PETER OTTO,KALOGERAKIS ARIS,MAYER SIMONA,PHILIPP ERIK,REIM STEFAN,SIEBER DIANA,SCHMITT J

申请号：

NZ61604512

公开号：

NZ616045A

申请日:

2012.03.28

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

Disclosed are Fe(III) complexes with bidentate pyrimidine ligands (formula I) and pharmaceutical compositions for use in the treatment and prevention of iron dificency and anaema. In comparison to classical preparations of Fe(II) salts, the complexes have fewer side effects, lower toxicity, low molecular weight, high complex stability and do not lead to free Fe which catalyses the formation of reactive oxygen species that cause oxidative stress.

来源网站：

中国工程科技知识中心

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