Preparation for use in the prevention and/or treatment of dementia syndromes, comprising the following fractions: a) long-chain polyunsaturated fatty acids comprising at least one of the É-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid; b) phospholipids, which fraction contains at least two different phospholipids, selected from the group consisting of phosphatidyl serine, phosphatidylinositol, phosphatidyl choline and phosphatidylethanolamine; c) compounds which are a factor in methionine metabolism, which fraction contains at least folic acid.