Andrew Thomas;Matthew C. Lucas;Roland Jakob-Roetne
发明人:
Roland Jakob-Roetne,Matthew C. Lucas,Andrew Thomas
申请号:
US12768762
公开号:
US08415379B2
申请日:
2010.04.28
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is concerned with isoxazole-pyridines of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as pharmaceuticals. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.