Austin L. GURNEY,Ming-Hong XIE,Julie Michelle RODA
申请号:
US15107841
公开号:
US20170044268A1
申请日:
2014.12.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides agents, such as soluble receptors, antibodies, and small molecules that modulate the immune response. In some embodiments, the agents activate or increase the immune response to cancer and/or a tumor. In some embodiments, the agents inhibit or suppress the immune response to cancer and/or a tumor. The invention also provides compositions, such as pharmaceutical compositions, comprising the agents. The invention further provides methods of administering the agents so a subject in need thereof. In some embodiments, the invention provides methods of using the agents for cancer immunotherapy. In some embodiments, the invention provides methods of using the agents for treatment of autoimmune diseases.