MODULATING PERMEABILITY OF THE BLOOD CEREBROSPINAL FLUID BARRIER

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专利权人:

MEMORIAL SLOAN-KETTERING CANCER CENTER

发明人:

Adrienne Boire,Joan Massague

申请号：

US15984087

公开号：

US20180334508A1

申请日:

2018.05.18

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention relates to methods and compositions for modulating the blood CSF barrier and for diagnosing, preventing and/or treating leptomeningeal metastasis. In particular embodiments of the invention, the permeability of the blood CSF barrier is modulated by agonists or antagonists of Complement Component 3 (C3) or its receptor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/