Systems and methods that enable delivery of radiofrequency energy and cryotherapy applications to adipose tissue for reduction and contouring of body fat are described herein. Aspects of the disclosure are directed to methods for reducing surface irregularities in a surface of a subject’s skin resulting from an uneven distribution of adipose tissue in the subcutaneous layer. The method can include delivering capacitively coupled or conductively coupled radiofrequency energy to a target region of the subject at a frequency which selectively heats fibrous septae in a subcutaneous layer of the target region to a maximum temperature less than a fibrous septae denaturation temperature. Furthermore, the method can include removing heat such that lipid-rich lobules in the subcutaneous layer are affected while non-lipid-rich cells and lipid-rich regions adjacent to the fibrous septae are not substantially affected.在此說明致使射頻能量與冷凍療法應用傳送到脂肪組織以用來減少並且雕塑體脂肪的系統與方法。本揭露的態樣係針對用來減少起因於皮下層脂肪組織之不均勻分佈之一受試者皮膚表面之表面不規則性的方法。該方法包括以將在目標區域之皮下層的纖維中隔選擇性地加熱到小於纖維中隔變性溫度之最大溫度的頻率、將電容性耦合或傳導性耦合射頻能量傳送到該受試者的目標區域。更者,該方法包括移除熱能,以致於在皮下層中的脂質豐富小葉會被影響,然而鄰近纖維中隔的非脂質豐富細胞以及脂質豐富區域則不會被實質影響。100...系統101...受試者/病人102...腹部區域104...組合模式治療裝置105...施加器106...治療單元107...射頻能量產生單元108a-b...流體線109a-b...射頻電力線110...供電器112...電線114...控制器116...控制線118...輸入裝置120...輸出裝置124...框架126...輪子
