JUHL, Karsten,MARIGO, Mauro,JESSING, Mikkel,LANGGÅRD, Morten,VITAL, Paulo Jorge Vieira,KEHLER, Jan,RASMUSSEN, Lars Kyhn,JUHL KARSTEN,MARIGO MAURO,JESSING MIKKEL,LANGGÅRD MORTEN,VITAL PAULO JORGE VIEIRA,KEHLER JAN,RASMUSSE
申请号：
CO2018010323
公开号：
CO2018010323A2
申请日:
2018.09.26
申请国别(地区):
CO
年份:
2018
代理人:
摘要：
The present Invention provides Summary 1.5 - dihydro - 4 - pyrazolo [3,4-d] pyrimidin-2-yl onas and 1.5 - 4 - dihydro - 4 - pyrazolo [43 - C] pyridin - 4 - onas of formula (i) as PDE1 inhibitors and their use as a Medicine, in particular for the treatment of neurodegenerative Disorders and Psychiatric Disorders.RESUMEN La presente invención proporciona 1,5-dihidro-4H-pirazolo[3,4-d]pirimidin-4-onas y 1,5-dihidro-4H-pirazolo[4,3-c]piridin-4-onas de fórmula (I) como inhibidores de PDE1 y su uso como un medicamento, en particular para el tratamiento de trastornos neurodegenerativos y trastornos psiquiátricos.
