It refers to a pharmacological synthesis, including a solid dosage form, including: (1) the first one, which is composed of hydrated ritonavir or salts with acceptable efficacy and water-insoluble polymer and / or water-soluble polymer; The second granule includes hydrate or pharmaceutically acceptable salt. He also mentioned a way to prepare the components of this pharmacology that would be useful in the treatment of HIV or AIDS.SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UNA FORMA DE DOSIFICACION SOLIDA QUE CONTIENE: I) UN PRIMER GRANULO QUE COMPRENDE HIDRATO DE RITONAVIR O UNA SAL FARMACEUTICAMENTE ACEPTABLE Y UN POLIMERO INSOLUBLE EN AGUA Y/O UN POLIMERO SOLUBLE EN AGUA; II) UN SEGUNDO GRANULO QUE COMPRENDE HIDRATO DE DARUNAVIR O UNA SAL FARMACEUTICAMENTE ACEPTABLE. SE REFIERE TAMBIEN A UN METODO DE PREPARACION DE DICHA COMPOSICION FARMACEUTICA, SIENDO DE UTILIDAD EN EL TRATAMIENTO DEL VIH O SIDA