Toshihiko Takeuchi;Sumant Ramachandra;Walter Robert Bishop;Chin-Yi Huang;Chao Bai Huang;Seema Kantak;Linda Masat
发明人:
Sumant Ramachandra,Walter Robert Bishop,Linda Masat,Chao Bai Huang,Toshihiko Takeuchi,Seema Kantak,Chin-Yi Huang
申请号：
US12739383
公开号：
US08216571B2
申请日:
2008.10.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed herein are fully human antibodies and antigen-binding fragments thereof that specifically bind human VEGF and inhibit VEGF binding to VEGF-R1 and VEGF-R2, and therefore inhibit VEGF signaling. The antibodies and antigen-binding fragments disclosed herein may be used, for example, to treat angiogenesis and conditions associated with angiogenesis both in vivo and in vitro.
