Sang Nam Kim;Young Chul Kim;Chul Ho Kang;Eun Ye Park
发明人:
Young Chul Kim,Chul Ho Kang,Eun Ye Park,Sang Nam Kim
申请号：
US13277605
公开号：
US08673371B2
申请日:
2011.10.20
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Disclosed is a composition for treating or preventing vitiligo or canities comprising Sophora japonica extract as an active ingredient. The Sophora japonica extract enhances melanin synthesis by increasing the activity of tyrosinase which is critical in intracellular melanin synthesis and promoting the expression of tyrosinase and TRP-2 mRNA. Furthermore, since the Sophora japonica extract is a natural substance with little cytotoxicity, it may be developed into a therapeutic agent for vitiligo and canities caused by depigmentation in skin and hair.
