ФОРМА МНОГОСЛОЙНОГО ПОКРЫТИЯ ФАРМАЦЕВТИЧЕСКОЙ КОМПОЗИЦИИ ДЛЯ ПЕРОРАЛЬНОГО ПРИМЕНЕНИЯ, СОДЕРЖАЩЕЙ ОМЕГА-3 ЖИРНУЮ КИСЛОТУ ИЛИ ЕЕ АЛКИЛОВЫЙ СЛОЖНЫЙ ЭФИР, А ТАКЖЕ ЛЕКАРСТВЕННОЕ СРЕДСТВО НА ОСНОВЕ СТАТИНА

• 收藏
• 分享

专利权人:

КУХНИЛЬ ФАРМ. КО.; ЛТД. (KR)

发明人:

ЧО Чжэ-Пьюн (KR),ЛЕЕ Пун-Сок (KR),ЛЕЕ Сыль-А (KR),ЧЖОН Мин-Хо (KR),ЛЕЕ Масе (KR)

申请号：

RU2014149010

公开号：

RU2014149010A

申请日:

2013.05.21

申请国别(地区):

RU

年份:

2016

代理人:

摘要：

1. A pharmaceutical composition for oral administration comprising: (a) core gelatin capsules containing omega-3 fatty acid or its alkyl ester (b) a first coating layer formed by coating the core gelatin capsule coatings based on hydroxypropyl methylcellulose and a copolymer of butyl methacrylate (2-dimethylaminoethyl) methacrylate and methyl methacrylate in a weight ratio of 1: 2: 1 and (c) a second coating layer formed by coating the first layer coating solution containing the medicament through statina.2. A pharmaceutical composition for oral administration according to Claim. 1, characterized in that the alkyl ester of an omega-3 fatty acid ester is the ethyl ester of omega-3 fatty kisloty.3. A pharmaceutical composition for oral administration according to claim 1, characterized in that the weight ratio of hydroxypropylmethylcellulose and a copolymer of butyl methacrylate, (2-dimethylaminoethyl) methacrylate and methyl methacrylate in a weight ratio of 1:. 2: 1 in the first coating layer ranges from about 1: 0, 8 to about 1: 10.4. A pharmaceutical composition for oral administration according to claim 3, characterized in that the weight ratio of hydroxypropylmethylcellulose and a copolymer of butyl methacrylate, (2-dimethylaminoethyl) methacrylate and methyl methacrylate in a weight ratio of 1:. 2: 1 in the first coating layer ranges from about 1: 1 to about 1: 9.5. A pharmaceutical composition for oral administration according to Claim. 1, characterized in that the coating solution containing the medicament through statin obtained by dissolving atorvastatin or its salts and at least1. Фармацевтическая композиция для перорального введения, содержащая:(a) ядро желатиновой капсулы, содержащее омега-3 жирную кислоту или ее алкиловый сложный эфир(b) первый слой покрытия, образованный посредством нанесения на ядро желатиновой капсулы покрытия на основе гидроксипропилметилцеллюлозы и сополимера бутилметакрилата, (2-диметиламиноэтил)метакрилата и метилметакрилата при

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/